#PRSJournalClub: A Year in Review and January #PRSJournalClub Wrap-Up – Risk Factor Analysis for Capsular Contracture, Malposition, and Late Seroma in Subjects Receiving Natrelle 410 Form-Stable Silicone Breast Implants

by Jordan D. Frey MD (@ChadPurnellMD), Chad A. Purnell MD (@ChadPurnellMD), and M. Shuja Shafqat MD (@shujashafqatmd)

This past month’s edition marked the one year anniversary of #PRSJournalClub since its inaugural unveiling in January 2016 discussing the article “Alar Contour Grafts in Rhinoplasty: A Safe and Reproducible Way to Refine Alar Contour Aesthetics” by Drs. Unger (@DoctorJacob), Roostaeian (@DrJasonPlastics), Small (@DrKevinSmall), Pezeshk, Lee, Harris, and Rohrich (@DrRodRohrich). Hosted by resident ambassadors Raj Sawh-Martinez (@docrfsm), Amanda Silva (@AmandaKSilvaMD), and Sammy Sinno (@sammysinnoMD, these monthly journal club selections certainly achieved the goal of generating worldwide discussion! As a reminder, each month PRS will post three #PRSJournalClub articles online for free. These are paired with a podcast discussion of each article hosted by the resident ambassadors joined by a guest expert plastic surgeon. One monthly #PRSJournalClub article is then chosen and discussed online via Twitter over a two-day period with the article’s authors.

We have all participated in departmental journal club events and recognize its benefits in fostering discussion and ultimate plastic surgery education. #PRSJournalClub is a collaborative forum in which the journal’s readership can directly interact with authors discussing their articles as well as plastic surgery issues in general. The goal of #PRSJournalClub is to bring together the Plastic and Reconstructive Surgery community, including readers, authors, attendings, residents, medical students, and even Editor-in-Chief, Dr. Rod Rohrich. I can still recall the shock of posting a question regarding septal cartilage harvest in primary rhinoplasty during the premier #PRSJournalClub and receiving a direct response from Dr. Rohrich!

Reflecting on one year of #PRSJournalClub, we are thrilled with its success thus far and are honored to begin a new year of connectivity, partnership, and sharing new, exciting articles from Plastic and Reconstructive Surgery. We encourage you to continue to read the free articles online, listen to the podcasts, and join in with the Twitter discussion (@PRSJournal) every month with the #PRSJournalClub! Lastly, at Plastic and Reconstructive Surgery, we seek to lead the way in multi-media connectivity in promoting plastic surgery as well as plastic surgery education. To this end, we are also introducing #PRSGrandRounds this year. For an introduction to #PRSGrandRounds, check out the following video link: https://www.facebook.com/pg/PRSjournal/videos/.

With this in mind, we began the new year with an exciting interactive discussion featuring the article “Risk Factor Analysis for Capsular Contracture, Malposition, and Late Seroma in Subjects Receiving Natrelle 410 Form-Stable Silicone Breast Implants” by Dr. Patricia McGuire (@PatMcGuireMD), Dr. Neil Reisman, and Diane Murphy from St. Louis. The article examined risk factors for occurrence of capsular contracture, malposition, and late seroma with Natrelle 410 implants in over 17,000 patients collected over multiple 10-year prospective, multicenter studies. With such robust patient capture and follow-up, this study provides incredible insight into outcomes with these unique devices for use in both reconstructive and aesthetic breast surgery.

The Natrelle 410 breast implant is tear-drop shaped, textured, and composed of highly cohesive silicone gel to limit mobility and reduce malrotation.  Cases were divided as into augmentation (n = 5059), revision-augmentation (n = 2632), reconstruction (n = 7502), or revision reconstruction (n = 2463). Capsular contracture events occurred 2.3% of the time in the augmentation cohort, 4.1% of the time in the revision-augmentation cohort, 3.1% of the time in the reconstruction cohort, and 4.0% of the time in the revision-reconstruction cohort. Meanwhile, malposition was reported in 1.5% of primary augmentation cases, 2.7% of revision-augmentation cases, 1.7% of primary reconstruction cases, and 2.7% of revision-reconstruction cases. Overall, seroma was identified >1 year after implantation in 31 of the 31,985 implants (0.1%) while four incidences of ALCL reported. Overall, the authors conclude that this data reaffirm the safety of Natrelle 410 implants while knowledge of risk factors for adverse outcomes offer guidance for reducing complications and optimizing outcomes.

The article was also supplemented by a PRS Journal Club podcast featuring Dr. Maurice Nahabedian (@DrMoSLS), which helped to launch the discussion on Twitter:

As you can imagine, this excellent paper fostered an excellent online, live Twitter dialogue between the authors and #PRSJournalClub followers from around the world! Check out below for just a sample of this fantastic discussion!

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap

2. January 2017 #PRSJournalClub Recap


Join us on Twitter for the NEXT PRS Journal Club’s Live Discussion:
Sunday and Monday, February 26th & 27th
@PRSJournal at #PRSJournalClub

 

REFERENCES

Risk Factor Analysis for Capsular Contracture, Malposition, and Late Seroma in Subjects Receiving Natrelle 410 Form-Stable Silicone Breast Implants” McGuire, Patricia; Reisman, Neal R.; Murphy, Diane K. Plastic & Reconstructive Surgery. 139(1):1-9, January 2017.

Listen to all of the previous PRS Journal Club Podcasts here: https://www.youtube.com/playlist?list=PLGj_TnyPrYXSPGtb6B5xreQS45Ps2O6Iz

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s